News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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University of Texas Researchers Reveal a Portable Cancer Detection Device with the Potential to Significantly Reduce the Number of Skin Biopsies Sent to Dermatopathologists

Team of bioengineers succeeds in putting three different imaging technologies into a handheld probe that could be used by physicians to assess skin lesions in their offices

Dermatopathologists and pathology practice administrators will be keenly interested in a new, hand-held diagnostic device that is designed to reduce the need for skin biopsies. Because of high volume of skin biopsies referred to pathologists, any significant reduction in the number of such case referrals would have negative revenue impact on medical laboratories  that process and diagnose these specimens.

This innovative work was done at the University of Texas at Austin’s Cockrell School of Engineering. The research team developed a probe that uses three different light modalities to detect melanoma and other skin cancer lesions in real-time, according to a news release.
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Researchers Produce First Map of Human Proteome, Generating Promise for Developing Novel Medical Laboratory Tests and New Therapeutics

The human proteome map provides a catalog of proteins expressed in nondiseased issues and organs to use as baseline in understanding changes that occur in disease

Given the growing importance of proteins in medical laboratory testing, pathologists will want to know about a major milestone recently achieved in this field. Researchers have announced that drafts of the complete human proteome have been released to the public.

Experts are comparing this to the first complete map of the human genome that was made public in 2000. Clinical laboratory managers and pathologists know how the availability of this information provided the foundation for rapid advances in understanding different aspects involving DNA and RNA.
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Clinical Chemists and Medical Laboratory Scientists Gather in Chicago for American Association of Clinical Chemistry and ASCLS Joint Meeting

Among the hundreds of lab industry vendors exhibiting, there were more companies showing LIS and lab informatics products this year than last year

CHICAGO, ILLINOIS—Anytime 20,000 clinical chemists and medical laboratory scientists gather in the same place, at the same time, there is sure to be many different opinions about the state of laboratory medicine and key trends in the clinical laboratory testing marketplace.

That was certainly true of this year’s annual meetings of the American Association of Clinical Chemistry (AACC) and the American Society of Clinical Laboratory Scientists (ASCLS) that took place here in the Windy City and ended yesterday. Your Dark Daily editor was in attendance and saw many interesting things during the exhibition, which opened on Tuesday and closed Thursday.

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Research Team at University of California Santa Barbara Achieves In Vivo Monitoring of Therapeutic Drugs with Technology That Pathologists Could Adapt for Clinical Diagnostic Purposes

Published study involved a demonstration of the MEDIC device’s ability to measure therapeutic drugs in animals, as well as human whole blood

Researchers at the University of California Santa Barbara (UCSB) are making rapid progress in designing a biosensor that can measure therapeutic levels of a prescription drug in real time within the patient. This technology has interesting implications for anatomic pathology and clinical laboratory testing.

The research team has developed a small electronic device that continuously tracks the level of medicines (doxorubicin and kanamycin) in an animal’s bloodstream. For pathologists and other physicians, this wireless tool can perhaps one day be used to help transform how drugs are chosen and monitored in patients. (more…)

Pathologists Could Have DNA Sequencing Device That Connects to a Smartphone and Can Produce Immediate Results from Several Types of Medical Laboratory Samples

At the proposed $1,000 price tag, Biomeme’ mobile clinical laboratory device has the potential to challenge diagnostic systems used in central laboratories

Another smartphone gadget capable of performing diagnostic laboratory tests is headed for the marketplace, and only time will tell if it proves to be a threat to the in vitro diagnostics industry.

Developers say that, when paired with a smartphone, this diagnostic device is similar to traditional medical laboratory technology 10 times its size. Called Biomeme, it is a system that  diagnoses diseases like a clinical laboratory—but is just the size of a can of cola. It can identify DNA signatures of bacteria or viruses in a sample of saliva, blood or urine, according to a story that appeared in the Philadelphia Inquirer. (more…)

New Plastic Artificial Cell with Working Organelles Could Be Adapted to Deliver Diagnostic Biomarkers Directly into Living Cells

Advances in artificial cell architecture and complex function may make it possible to develop a way for pathologists to deliver biomarkers into living cells to diagnosis diseases and monitor patient response to therapies

For the first time, researchers have used polymers to produce an artificial eukaryotic cell with working organelles. Like a living cell, it successfully performed multiple chemical reactions. The importance for pathologists and clinical laboratory professionals is that the same technology could allow scientists to develop different ways to deliver biomarkers into cells to reveal diagnostic information—and perhaps even track a patient’s progress in therapy.

Dutch Researchers Get Closer to Unlocking the Complexity of a Living Cell
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