News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
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Clinical Laboratories Could Soon Diagnose 17 Diseases with a Single Breath Analyzer Test from Israel’s Institute of Technology

The Technion breathalyzer would give pathology groups and medical laboratories unprecedented ability to support physicians in diagnosing and treating cancers, chronic diseases, and other illnesses

Readers of Dark Daily know that several pathology research teams in America and the UK are developing breath analyzer tests that can detect everything from lung cancer to early-stage infections. Clinical laboratories will soon have a plethora of breath-related tests from which to choose. Now there’s a new kid on the block. A breathalyzer test that can detect up to 17 distinct cancerous, inflammatory, and neurological diseases!

Assuming the cost per test was at a competitive level to existing technologies, what would give this new diagnostic system appeal to physicians and patients alike is that it would be a non-invasive way to diagnose disease. Only a sample of the patient’s breath would be needed to perform the assays.

Researchers at the Israel Institute of Technology, or Technion, published the results of their study in ACS Nano, a monthly journal of the American Chemical Society devoted to “nanoscience and nanotechnology research at the interfaces of chemistry, biology, materials science, physics, and engineering.” (more…)

Unstructured Data Is a Target for New Collaboration Involving IBM’s Watson Health and Others; Could Help Pathologists and Radiologists Generate New Revenue

If this medical imaging collaborative develops a way to use the unstructured data in radiology images and anatomic pathology reports, it could create a new revenue stream for pathologists

Unstructured data has been regularly recognized as one Achilles heel for the anatomic pathology profession. It means invaluable information about the cancers and other diseases diagnosed by surgical pathologists are “locked up,” making it difficult for this information to be accessed in efforts to advance population health management (PHM) or conduct clinical studies.

Similarly, medical imaging has an essential role in the diagnosis of cancer and other diseases. And, like most anatomic pathology reports, medical imaging also is considered to be “unstructured” by data experts because it is not easily accessible by computers, reported Fortune magazine.

Unstructured Data in Anatomic Pathology and Radiology

Now one of the world’s largest information technology companies wants to tackle the challenge of unstructured data in radiology images. IBM (NYSE: IBM) Watson Health launched a global initiative involving 16 health systems, radiology providers, and imaging technology companies.

The Watson Health medical imaging collaborative is working to apply cognitive computing of radiology images to clinical practice. IBM aims to transform how physicians use radiology images to diagnose and monitor patients. (more…)

Biotech Entrepreneur Ready to Spend $100 Million to Design Cheap and Easy-to-Use Handheld Ultra-sound Scanners That Can be Used in Drugstores

Radiology poised to be disrupted as entrepreneurs work to create smaller, cheaper imaging devices that perform as well or better than big, expensive imaging systems

Handheld ultra-sound scanners that are as “cheap as a stethoscope” is the goal of a $100 million development project. Just as the clinical laboratory industry is seeing entrepreneurs pour hundreds of millions of dollars into projects intended to create miniature medical laboratory testing devices, so also is radiology and imaging a target for ambitious entrepreneurs.

The vision of biotechnology entrepreneur Jonathan Rothberg, Ph.D. is to have patients take a trip to their neighborhood drugstore rather than an imaging center the next time they need an ultrasound or MRI.

Rothberg is the driving force behind a $100 million startup called Butterfly Network. He hopes to disrupt the status quo in radiology by creating an ultrasound scanner that “is as cheap as a stethoscope” and would allow physicians or other healthcare professionals to do imaging studies using a device not much larger than a smartphone, MIT Technology Review reports. (more…)

Mathematical Modeling of Systems Pharmacogenetics by Researchers at Penn State May Create New Opportunities for Clinical Pathology Laboratories

Goal is to apply differential equations with pharmacogenomics to better predict a patient’s response to prescription drugs, a development that could create role for pathologists to help clinicians interpret the data from such medical lab testing

New approaches to mathematical modeling are poised to transform pharmaceutical drug research and development—and create new opportunities in clinical laboratory testing down the road. U.S. and Chinese scientists have developed statistical models that more accurately simulate a drug’s reaction in a patient.

Using differential equations, these researchers seek to integrate mathematical modeling of drug reactions into pharmacogenomics. Their goal is to better predict interpersonal differences in drug response based on genetic information. This will help clinicians to develop a strategy for personalized drug delivery. (more…)

23andMe and Udacity Launch ‘Massive Online Open Course’ in Human Genetics

Innovative web-based educational formats might add value to training initiatives for pathology residents and fellows and medical laboratory workers

In the final months of 2013, the regulatory fight between gene testing company 23andMe.com and the Food and Drug Administration (FDA) generated national headlines. In that encounter, 23andMe.com blinked and ceased offering health-related genetic tests to consumers.

However, the company continues to work to position itself as a major player in genetic testing and genetic medicine. In the second half of 2013, for example, 23andMe.com initiated a business campaign to position itself as a source of on-line information about genetics for educational purposes. (more…)

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