Feb 5, 2016 | Laboratory Pathology, Laboratory Testing
Called ‘ViroCap,’ this new diagnostic technology is able to discover more viruses in patient samples, as compared to PCR genome sequencing tests
It could be the ultimate multi-analysis medical laboratory test ever. Researchers at Washington University School of Medicine in St. Louis have developed a diagnostic test that they claim tests for any virus infecting people and animals.
The new test, called ViroCap, detects viruses that standard tests based on genome sequencing cannot, according to a university statement.
Viruses Make for a Popular Research Subject
Are virus tests going, well, viral? It was just a few weeks ago that Dark Daily reported on research at Howard Hughes Medical Institute (HHMI) aimed at unlocking virus detection beyond one pathogen at a time. (See Dark Daily, “Researchers at Howard Hughes Medical Institute Develop Blood Test That Reveals a Patient’s Viral History; Could Reduce Unnecessary Clinical Laboratory Testing,” December, 30, 2015.)
The HHMI research resulted in VirScan, an alternative to medical laboratory tests that test for specific viruses one at a time, and which can detect all diseases a patient has had over his or her lifetime, according to an HHMI news statement about the new technology. (more…)
Dec 30, 2015 | Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Operations, Laboratory Pathology, Laboratory Testing
The VirScan test gives doctors insight into a patient’s lifetime exposure to viruses and thus may be developed into a useful medical laboratory test
Scientists and pathologists are learning that blood is like a time capsule, holding precious information about exposure to viruses over the years—chickenpox at five, mononucleosis at 18, flu at 40. You get the idea.
Now, researchers at Howard Hughes Medical Institute (HHMI) have found a way to tap that entire data stream, so to speak. An inexpensive blood test, they say, reveals every virus that has passed through the body over time.
New Discoveries Could Lead to a Useful Clinical Laboratory Test
The testing method, called VirScan by researchers, is an efficient alternative to current medical laboratory tests that test for specific viruses one at a time, according to an HHMI news statement about the new technology. (more…)
Dec 11, 2015 | Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory Management and Operations, Laboratory Pathology, Laboratory Testing
Researchers demonstrate that the length of blood telomeres may follow a specific pattern before cancer is detectable, which could lead to new diagnostic tests for detecting cancer in its early stages
Pathologists and Clinical pathology laboratories could soon have another tool to aid in the early detection of cancer. New research findings indicate that telomeres could serve as biomarkers for cancer if the right testing is done at the right times.
This study was conducted by Northwestern Medicine, (a collaboration between Northwestern Memorial HealthCare and Northwestern University Feinberg School of Medicine) and Harvard University. It was titled “Blood Telomere Length Attrition and Cancer Development in the Normative Aging Study Cohort”. The findings bring scientists a step closer to understanding how telomeres change with the onset of cancer.
Predictive Biomarker for Cancer Might Be Used in Clinical Lab Testing
“Understanding this pattern of telomere growth may mean it can be a predictive biomarker for cancer,” said Lifang Hou, MD, PhD, the study’s lead author and a professor of preventive medicine at Northwestern University Feinberg School of Medicine in a Northwestern Medicine news release. “Because we saw a strong relationship in the pattern across a wide variety of cancers, with the right testing these procedures could be used to eventually diagnose a wide variety of cancers.” (more…)
Nov 27, 2015 | Compliance, Legal, and Malpractice, Laboratory Management and Operations, Laboratory News, Laboratory Operations, Laboratory Pathology, Management & Operations
Newspapers in this populous nation regularly publish stories about clinical laboratories that produce inaccurate lab test results that cause patient harm
In the healthcare systems of many countries across the globe, one common issue involves the accuracy and reliability of medical laboratory test results produced by clinical pathology laboratories. In most of these countries, a lack of effective government regulation is a primary reason why shady lab operators continue to provide questionable lab test results to patients.
In India, professionally-trained pathologists and laboratory scientists have repeatedly called for tougher government regulation of medical laboratories, along with more diligent inspections and enforcement actions by the authorities. Newspapers in India regularly publish stories of the medical lab enforcement actions that do happen. (more…)
Nov 13, 2015 | Laboratory Instruments & Laboratory Equipment, Laboratory News, Laboratory Operations, Laboratory Pathology, Laboratory Testing, Management & Operations
Lab-on-a-chip technology could reduce the time needed to identify infection-causing bacteria and for physicians to prescribe correct antibiotics
Pathology groups and medical laboratories may see their role in the patient-care process grow if researchers succeed in developing culture-independent diagnostic tools that quickly identify bacterial infections as well as pinpoint the antibiotics needed to treat them.
In the battle against antibiotic-resistant infections (AKA “super bugs”) the National Institutes of Health (NIH) is funding nine research projects aimed at thwarting the growing problem of life-threatening infections that no longer are controlled or killed by today’s arsenal of drugs.
Common Practices in Hospitals Leading to Super Bugs
Currently, when infections are suspected in hospitals or other settings where illness can quickly spread, samples are sent to a central medical laboratory where it may take up to three days to determine what germ is causing the infection. Because of that delay, physicians often prescribe broad-spectrum antibiotics based on a patient’s symptoms rather than lab test results, a practice that can lead to the growth of antibiotic-resistant microbes. (more…)
