May 15, 2017 | Digital Pathology, Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Operations, Laboratory Pathology
Low-cost assay would be a boon in remote areas, war zones, and emergency departments by providing fast and reliable blood typing without the need for specialized clinical lab equipment, and by reducing demand on type-O blood supplies
Chinese researchers claim to have invented an inexpensive point-of-care (POC), paper-based blood test that can determine a patient’s blood type in seconds and with nearly perfect accuracy.
Such an inexpensive, simple-to-use assay would be game changing for pathology groups and clinical laboratories since traditional tests to classify blood into blood groups remain time consuming and labor intensive despite recent advances.
Changing Colors Reveal Blood Type
Hong Zhang and colleagues at Third Military Medical University in Chongqing, China, published their results in the March 15, 2017, issue of Science Translational Medicine. (more…)
Oct 19, 2016 | Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory News, Laboratory Operations, Laboratory Pathology, Laboratory Testing
Engineers have designed a microfluidics and nano-scale diagnostic toolkit suitable for attaching directly to muscle and tissue to monitor biomarkers and stream results wirelessly to care providers and medical laboratories
What would change in medicine if physicians had sutures that could collect and report biomarker data, including the kinds of biomarkers that are used in clinical laboratory tests? Such a product may be feasible, based on newly-published research.
“Smart sutures” are a joint project between Tufts University, Harvard University, and Massachusetts Institute of Technology (MIT) engineers. They announced a thread-based diagnostic device (TDD) system capable of detecting biomarkers and analytes using 3D sutures composed of cotton and synthetic threads.
Processing the cotton and synthetic threads in various ways enhances their natural properties. The toolkit of different sutures developed by the team has exhibited a range of uses—including measuring physical stress at an incision, monitoring pH of tissues and fluids, and measuring glucose. (more…)
Jan 8, 2016 | Digital Pathology, Instruments & Equipment, Laboratory News, Laboratory Operations, Laboratory Pathology, Management & Operations
Pathologists will be interested to learn that this latest version of the acoustic tweezer device requires about five hours to identify the CTCs in a sample of blood
Medical laboratory leaders and pathologists are well aware that circulating tumor cells (CTCs) released by primary tumors into the bloodstream are fragile and easily damaged. Many studies have sought to find ways to separate CTCs from surrounding cells. Such a process could then be used as an early-detection biomarker to detect cancer from a sample of blood.
One team of researchers believe it has a way to accomplish this. These researchers are using sound waves to gently detect and isolate CTCs in blood samples. In turn, this could make it possible to diagnose cancer using “liquid biopsies” as opposed to invasive conventional biopsies.
Researchers from Carnegie Mellon University (CMU) in collaboration with researchers from the Massachusetts Institute of Technology (MIT) and Pennsylvania State University (Penn State) have developed a method for using acoustic tweezers and sound waves to separate blood-borne cancer cells from white blood cells. The research team believes this new device could one day replace invasive biopsies, according to a CMU article. (more…)
Jan 28, 2015 | Digital Pathology, Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Pathology, Management & Operations
Innovative device uses acoustic sound waves to gently separate circulating cancer cells from white blood cells
In many respects, the ability to separate and identify circulating tumor cells (CTCs) is one of the holy grails of cancer diagnostics. It is widely believed that a clinical laboratory test that can effectively identify CTCs would contribute to earlier detection of cancer and improved outcomes for caner patients.
Pathologists will be interested to learn about a useful new tool that can flag circulating tumor cells. Researchers say that this approach enables them to determine if a cancerous tumor is going to spread, without tagging tumor cells with harsh chemicals. This gentler alternative to current diagnostic methods involves an innovative device that uses “tilted” sound waves to sort tumor cells from white blood cells, noted a report in Headlines & Global News.
This device is about the size of a cell phone. It was developed by a team of scientists from the Pennsylvania State University (PSU), Massachusetts Institute of Technology (MIT) and Carnegie Mellon University (CMU).
Their research was funded by the National Institutes of Health (NIH) and the National Science Foundation (NSF). The research study was published by PNAS, the journal of the U.S. National Academy of Sciences, January 5, 2015. (more…)
Jan 26, 2015 | Digital Pathology, Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Pathology, Management & Operations
The advent of the CRISPR/Cas9 genetic editing tool is already generating novel therapies for diseases and will create new opportunities for pathologists and medical laboratories
In just 24 months, a new gene-editing tool has become the hot topic worldwide among researchers working to understand DNA and develop ways to manipulate it for therapeutic purposes. It goes by the acronym CRISPR and it may soon become quite familiar to most pathologists and medical laboratory scientists.
CRISPR stands for clustered regularly interspaced short palindromic repeats. The gene editing platform is known as CRISPR/CAS9. (more…)
