May 24, 2013 | Digital Pathology, Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory News, Laboratory Operations, Laboratory Pathology
New discoveries demonstrate important advantages of whole-genome sequencing in investigations of DNA ‘dark matter’ and shed light on the possible origins of cancer
Whole-genome scanning of cancer cells revealed significant mutations in the “dark matter” areas of melanoma DNA. This represents a leap forward in the basic science of cancer. Easier access to whole-genome sequencing means that researchers are poised to mine a rich vein of data that will shine a light on how cells malfunction.
For pathologists and clinical laboratory managers, these new research findings hold the promise to open up another approach to using the data in whole human genomes for diagnostic and therapeutic purposes. It also shows one more practical outcome from the rapidly falling cost of sequencing DNA. (more…)
Jan 7, 2013 | Digital Pathology, Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory Management and Operations, Laboratory News, Laboratory Pathology
Existing unstructured anatomic pathology reports would directly benefit from novel word disambiguation approach under development at MIT
Unstructured medical laboratory data is widely recognized to be one significant hurdle on the path toward the universal electronic health record (EHR). This is particularly true for anatomic pathology reports. Despite advances in synoptic reporting, to date, few pathology groups and clinical laboratories have developed ways to resolve this problem.
Now there is news of a different approach toward unstructured healthcare data. Researchers at the Massachusetts Institute of Technology (MIT) have developed a system for algorithmically distinguishing words with multiple possible meanings. The new approach could help find useful information buried in electronic medical records (EHR). (more…)
Jan 18, 2012 | Instruments & Equipment, Laboratory Instruments & Laboratory Equipment, Laboratory News, Laboratory Pathology, Management & Operations
Clinical laboratory directors and pathologists will see threats and opportunities as microelectronic devices offer new diagnostic and therapeutic modalities
In vivo clinical diagnostic testing just took a giant step forward. A team of medical engineers at the Technical University of Munich (TUM) have developed a prototype microchip sensor implant designed to continuously monitor tumors remotely.
Internal Detection Device Allows For Remote Monitoring In Real Time
The device, called IntelliTuM (Intelligent Implant for Tumor Monitoring), detects the level of dissolved oxygen in the fluid near the tumor, according to an online article at Technology Review, published by Massachusetts Institute of Technology.
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Nov 29, 2011 | Laboratory News, Laboratory Operations, Laboratory Pathology
Advances in use of probe-based Confocal Laser Endomicroscopy (pCLE) could mean that GIs refer fewer specimens to clinical pathology laboratories
Gastroenterologists are beginning to use what is being called the “world’s smallest microscope” to view tissue in situ and diagnose disease. It is a technology innovation that will have important ramifications for the anatomic pathology profession because this new system is designed to allow physicians to microscopically examine a patient’s GI tissue at the cellular level in its natural environment.
The product is entering clinical use in the United States. It is called Cellvizio and is manufactured by Mauna Kea Technologies (MKEA), a French company with offices in Newtown, Pennsylvania. Cellvizio is a miniature microscope that, once inserted into the GI tract, enables the physician to select cells for microscopic examination in order to make a more immediate decision regarding a diagnosis, as well as treatment.
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Sep 26, 2011 | Uncategorized
Clinical and anatomic pathology laboratories may soon find next-generation DNA sequencing reliable and affordable
Swift advances in whole human genome sequencing may bring clinical applications to pathology on a much faster timeline than expected.
One impressive example of the fast pace of technology improvements is the Ion Torrent, which is a semiconductor-based DNA sequencer now capable of sequencing 100 million base pairs. That is ten times the sequencer’s capacity when it was launched just last December!
It was August of last year when Life Technologies (NASDAQ: LIFE) in Carlsbad, California, paid $375 million to acquire Ion Torrent Systems, a start-up with operations in Guilford, Connecticut, and South San Francisco. If Ion Torrent achieves certain technical milestones through 2012, it will earn another $350 million.
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