News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel

News, Analysis, Trends, Management Innovations for
Clinical Laboratories and Pathology Groups

Hosted by Robert Michel
Sign In

Major Healthcare Systems Begin Building In-House Whole Human Genome Sequencing Capabilities, Creating New Opportunities for Pathologists

Partners HealthCare and Geisinger Health are among health systems making investments and developing the clinical utility of genome sequencing

Next-generation gene sequencing is making fast inroads among the nation’s largest academic centers and health systems. This is an auspicious development for the clinical laboratory industry. It positions pathologists to play a greater role in clinical care and genetic medicine.

News accounts and published research suggest that mega systems—including Partners HealthCare, Geisinger Health System, Scripps Health, and Medical College of Wisconsin—are among first movers investing in genome-sequencing equipment and assembling the medical expertise necessary to establish genetic-testing programs and help physicians utilize gene sequences where appropriate for patient care. (more…)

Anticipating the Digital Medicine Revolution, Scripps Doctor Prescribes Smartphone Apps as Frequently as Medications

Pathologists will want to engage with physicians as wireless devices and smartphone apps make it possible to maintain continuous surveillance of the body

Pathologists might want to borrow a page from a tech-savvy doctor who was voted the “Most Influential Physician Executive” in 2012. A cardiologist, this physician says he now prescribes mobile applications for his patients almost as frequently as he prescribes therapeutic drugs.

Many clinical laboratory managers will recognize the name of Eric Topol, M.D., who is the Director of the Scripps Translational Science Institute, Professor of Genomics at the Scripps Research Institute, and Chief Academic Officer at Scripps Health, all located in La Jolla, California. Topol has a passion for wireless medical technology. Moreover, he is nationally recognized as a wireless medical technology trailblazer, as well as for his medical expertise.

In fact, in one news clip, NBC News touts him as the nation’s foremost expert in the explosion of wireless medicine. Topol was also selected by GQ Magazine in 2009 as one of the nation’s 12 “Rock Stars of Science.” (more…)

New iPhone App Allows Consumers to Test Their Urine on the Go for as Many as 25 Different Diseases

Pathologists and clinical laboratory managers may want to learn more about the UCheck mobile app developed by Biosense Technologies  

Developers of a new iPhone application claim their app can analyze a urine specimen for up to 25 different diseases. This mobile app is a deliberate attempt to give consumers the ability to perform diagnostic tests that would normally be run in a full-scale clinical laboratory.

Pathologists and clinical biochemists will want to visit the website of Biosense Technologies to check out this mobile application, which is called uCheck. Biosense is a medical device company located in Mumbai, India. (more…)

Geneticists Question Balance of Media Coverage of the Value of Gene Sequencing and Personalized Medicine

Pathologists and medical laboratory managers will want to stay informed about how genome sequencing data is being translated into clinical applications

There is a vigorous debate unfolding about the ability of personal genome sequencing to reliably predict disease. That is not news to pathologists and clinical laboratory managers. What is a novel twist in the arguments by both sides is whether media coverage has the potential to undermine public support for genomics and personalized medicine.

For example, one media story on a study of the power of personal genome sequencing to predict disease drew fire from some genomics experts on two counts. First, they questioned the validity of the study. Second, they fear that such coverage by the media could weaken public support for genomics and personalized medicine.

Public Perception of the Value of Genetic Testing

During 2012, The New York Times published a story on a study by Johns Hopkins University that sought to determine whether genetic testing can predict future disease. According to the results of this particular study, it cannot.

Some noted genomics experts took the Times—and the study—to task. One is Ronald W. Davis, Ph.D., Professor of Biochemistry and Genetics at Stanford University School of Medicine. Davis is Director of the Stanford Genome Technology Center. (more…)

Scripps Physicians Call for Shift in how Clinical Pathology Laboratories Process Cancer Tissue Samples

Pathologists and clinical laboratory managers should fundamentally change how cancer specimens are handled

Three physicians at Scripps Health are calling for pathologists to rethink how they collect and store cancer tissue samples in two significant ways. They say that pathologists need to: 1) move away from formalin-fixed, paraffin-embedded (FFPE) tissue blocks and toward frozen samples; and, 2) start collecting larger samples.

These doctors used the Journal of the American Medical Association as a platform to issue their call for a change in what has been a long-standing standard of practice in anatomic pathology. Given the progressive nature of these opinions, there will certainly be dissenting voices within the pathology profession who are likely to add their voices to this debate.

(more…)

;